Content:

1. Introduction: the relevance of natural products as sources of new drugs; historical

aspects; the “golden age” of antibiotics; sources of natural products and examples;

2. Natural products discovery I: sample collection; culture; extraction; bioassay-guided

fractionation;

3. Natural products discovery II: purification; residual complexity; structure elucidation;

4. Challenges and innovations: challenges in the natural product discovery process;

technological innovations; dereplication;

5. Omics techniques: metabolomics and genomics applied to natural products.

For more information, search for code FBT5712 on the USP Course Catalog