Articles & book chapters

Médice, R.V., Arruda, R.N., Yoon, J., Crnkovic, Borges, R.M., Noyma, N.P., Lürling, M., Crnkovic, C.M., Marinho, M.M., Pinto, E. Unlocking Biological Activity and Metabolomics Insights: Primary Screening of Cyanobacterial Biomass from a Tropical Reservoir. Environmental Toxicology and Chemistry (2024) 43(10):2222-2231

Campos, T.G.V., Gama, W.A., Geraldes, V., Yoon, J., Crnkovic, C.M., Pinto, E., Jacinavicius, F.R. New records on toxic cyanobacteria from Brazil: Exploring their occurrence and geography. Science of The Total Environment (2024) 931:172689

Crnkovic, C.M, Silva, F.H.S., Amorim, H.M.M. Prospecção de metabólitos secundários bioativos. In: Fiamoncini, J., Demarque, D.P., Crnkovic, C.M. (eds) Fitoquímicos em alimentos, fármacos e medicamentos. Manole, Santana de Parnaíba [SP] (2023), pp 238-261.

Fiamoncini, J., Demarque, D.P., Crnkovic, C.M. Fitoquímicos em alimentos, fármacos e medicamentos. Manole, Santana de Parnaíba [SP] (2023), 326 pp.

Weiss, M.N., Médice, R.V., Jacinavicius, F.R., Pinto, E., Crnkovic, C.M. Metabolomics applied to cyanobacterial toxins and natural products. In: Pacheco Fill, T. (ed) Microbial Natural Products Chemistry. Advances in Experimental Medicine and Biology. Springer, Cham (2023), vol 1439, pp 21–49.

Souza, K.S., Silva, M.R.F., Araújo, L.C.A, Silva, K.C.C., Silva, F.H.S., Crnkovic, C.M., Motteran, F.,Oliveira, M.B.M. Impacts of the Pesticides on Urban Aquatic Ecosystems and Their Regulation Measures. In: Singh, R., Singh, P., Tripathi, S., Chandra, K.K., Bhadouria, R. (eds) Xenobiotics in Urban Ecosystems. Springer, Cham (2023), pp 391–398.

Silva, M.R.F., Souza, K.S., Silva, F.H.S., Crnkovic, C.M., Motteran, F., Araújo, L.C.A, Oliveira, M.B.M. Bioremediation Strategies for Microplastic Removal in Impacted Aquatic Environments. In: Singh, R., Singh, P., Tripathi, S., Chandra, K.K., Bhadouria, R. (eds) Xenobiotics in Urban Ecosystems. Springer, Cham (2023), pp 341–351.

Michaliski, L.F., Ióca, L.P., Oliveira, L.S., Crnkovic, C.M., Takaki, M., Freire, V., Berlinck, R.G.S. Improvement of Targeted Fungi Secondary Metabolite Production Using a Systematic Experimental Design and Chemometrics Analysis. Methods and Protocols (2023) 6(5):77.

Oliveira, L.S., Crnkovic, C.M., Amorim, M.R., Navarro-Vázquez, A., Paz, T.A., Freire, V., Takaki, M., Venâncio, T., Ferreira, A.G., Saito, R.F., Chammas, R., Berlinck, R.G.S. Phomactinine, the First Nitrogen-Bearing Phomactin, Produced by Biatriospora sp. CBMAI 1333. Journal of Natural Products (2023), 86(8):2065–2072.

Jacinavicius, F.R., Geraldes, V., Fernandes, K., Crnkovic, C.M., Gama, W.A., Pinto, E. Toxicological effects of cyanobacterial metabolites on zebrafish larval development. Harmful Algae (2023) 125:102430

Borges, R. M., das Neves Costa, F., Chagas, F. O., Teixeira, A. M., Yoon, J., Weiss, M. B., Crnkovic, C. M., Pilon, A. C., Garrido, B. C., Betancur, L. A., Forero, A. M., Castellanos, L., Ramos, F. A., Pupo, M. T., Kuhn, S. Data Fusion‐based Discovery (DAFdiscovery) pipeline to aid compound annotation and bioactive compound discovery across diverse spectral data. Phytochemical Analysis (2023) 34(1):48-55

Berlinck, R.G.S., Crnkovic, C.M., Gubiani, J.R., Bernardi, D.I., Ióca, L.P., Quintana-Bulla, J.I. The isolation of water-soluble natural products – challenges, strategies and perspectives. Natural Product Reports (2022) 39:596-669

Tonon, L.A.C, Rua, C., Crnkovic, C.M., Bernardi, D.I., Pires Junior, O.R., Haddad, C.F.B., Pedrosa, C.S.G., Souza, L.R.Q., Rehen, S.K., Azevedo, G.P.R., Thompson, C.C. Thompson, F.L., Berlinck, R.G.S. Microbiome associated with the tetrodotoxin-bearing anuran Brachycephalus pitanga. Toxicon (2021) 203:139-146

Crnkovic, C.M., Caricati, C.P., Oliveira, R.P.S., Stephano, M.A. Biosafety applied in pharmaceutical and biotechnological processes. In: Pharmaceutical Biotechnology; Pessoa Jr, A., Vitolo, M., Long, P.F., Eds.; CRC Press/Taylor & Francis Group: Boca Raton, 2021; pp 313-324

Ióca, L.P., Dai, Y., Kunakom, S., Santos Júnior, P.L.T, Diaz-Espinosa, J., Krunic, A., Crnkovic, C.M., Orjala, J., Sanchez, L.M., Ferreira, A. G., Berlinck, R.G.S., Eustáquio, A.S. A novel family of nonribosomal peptides modulate collective behavior in Pseudovibrio bacteria isolated from marine sponges. Angewandte Chemie (2021) 60(29):15891-15898

Costa, J.H., Bazioli, J.M., Barbosa, L.D., Santos Júnior, P.L.T, Reis F.C.G., Klimeck, T., Crnkovic, C.M., Berlinck, R.G.S., Sussulini, A., Rodrigues, M.L., Fill, T.P. Phytotoxic tryptoquialanines produced in vivo by Penicillium digitatum are exported in extracellular vesicles. MBio (2021) 2(1): e03393-20 

Jacinavicius, F.R., Geraldes, V., Crnkovic, C.M., Delbaje, E., Fiori, M., Pinto, E. Effect of ultraviolet radiation on the metabolomic profiles of potentially toxic cyanobacteria. FEMS Microbiol Ecol (2021) 1:fiaa243

May, D.S., Crnkovic, C.M., Krunic, A., Wilson, T.A., Fuchs, J.R., Orjala, J. 15N stable isotope labeling and comparative metabolomics facilitates genome mining in cultured cyanobacteria. ACS Chem Biol (2020) 15(3):758-765

Crnkovic, C.M., Braesel, J., Krunic, A., Eustáquio, A.S., Orjala, J. Scytodecamide from the Cultured Scytonema sp. UIC 10036 Expands the Chemical and Genetic Diversity of Cyanobactins. ChemBioChem (2020). 21(6):845-852

Prior to Jan, 2020

Guo Y*, Crnkovic CM*, Won KJ, Yang X, Lee JR, Orjala J, Lee H, Jeong H. Commensal gut bacteria convert the immunosuppressant tacrolimus to less potent metabolites. Drug Metab Dispos (2019) 47(3):194-202

Crnkovic CM, Krunic A, May DS, Wilson, TA. Kao D, Burdette JE, Fuchs JR, Oberlies NH, Orjala J. Calothrixamides A and B from the cultured cyanobacterium Calothrix sp. UIC 10520. J Nat Prod (2018) 81(9):2083-2090

Braesel J, Crnkovic CM, Kunstman K ,Green S, Maienschein-Cline M, Orjala J, Murphy BT, Eustaquio AS. Complete genome of Micromonospora sp. strain B006 reveals biosynthetic potential of a Lake Michigan actinomycete. J Nat Prod (2018) 81(9):2057-2068

Crnkovic CM, May DS & Orjala J. The impact of culture conditions on growth and metabolomic profiles of freshwater cyanobacteria. J Appl Phycol (2018) 30(1):375-384